Seattle doctors developed a blood test that determines the parental origin of the RB1 mutation in retinoblastoma.

A new research paper was published in Volume 16 of Genes & Cancer on January 20, 2025, entitled, "Analysis of pathogenic variants in retinoblastoma reveals a potential gain of function mutation." ...

Scott Brocato recently spoke with Dr. Claudia Prospero Ponce, a neuro-ophthalmologist and ocular pathologist with Texas Tech ...

But THE OSU's seventh natty was deserved after it won its four playoff games by double-digit margins. That run was capped ...

Esophageal squamous cell carcinoma (ESCC) is a severe health threat, being a predominant subtype of esophageal cancer and contributing significantly to cancer-related mortality globally.

Furthermore, gene set enrichment analysis shows repression of the androgen ... and CDK4 and CDK6 mediate the G1-S phase transition through phosphorylation of RB1. Successful inhibition of CDK4/6 ...

Alterations in this gene can disrupt proper protein folding and membrane localization ... Losses in tumor suppressor genes such as RB1 and CDKN1B further highlight the genomic instability of this ...

The inherited mutated gene WNT9B, which functions normally in embryonic prostate development, increases risk of adult prostate cancer, according to a new study.